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It is not known whether Diovan is excreted in human milkDiovan was excreted in the milk of lactating ratshoweveranimal breast milk drug levels may not accurately reflect human breast milk levelsBecause many drugs are excreted into human milk and because of the potential for adverse reactions in nursing infants from Diovana decision should be made whether to discontinue nursing or discontinue the drugtaking into account the importance of the drug to the mother.

Be careful drivingoperating machinery or doing jobs that require you to be alert while you are taking Diovan until you know how it affects you.

Although the overall morbidity result favored valsartanthis result was largely driven by the 7of patients not receiving an ACE inhibitoras shown in the following table.

The results from an in vitro study with human liver tissue indicate that valsartan is a substrate of the hepatic uptake transporter OATP1B1 and the hepatic efflux transporter MRP2Coadministration of inhibitors of the uptake transporterrifampincyclosporineor efflux transporterritonavirmay increase the systemic exposure to valsartan.

Dual blockade of the RAS with angiotensin receptor blockersACE inhibitorsor aliskiren is associated with increased risks of hypotensionhyperkalemiaand changes in renal functionincluding acute renal failurecompared to monotherapyMost patients receiving the combination of two RAS inhibitors do not obtain any additional benefit compared to monotherapysee Clinical TrialsIn generalavoid combined use of RAS inhibitorsClosely monitor blood pressurerenal function and electrolytes in patients on Diovan and other agents that affect the RAS.

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meantime while i was waiting an approval for diovan i went into what the nyse called was medical shock i can t remember the actual term but what happened is that i had been with out medication for so long that i couldn t get out of bed, my head was pun ding it felt as if it was going to burst, i was having triple vision and virtigo, vomiting etc.

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